AnalysisScienceNovember 6, 2026

Paper benchmarks protein motif scaffolding on dynamic stability

Read original source →arxiv.org

New benchmarks BILBY-PRO and BILBY-MD use all-atom molecular dynamics to test scaffold-generation models like RFDiffusion, Proteina and ESM3 on dynamic fidelity, not just static success. The work tracks motif drift, scaffold drift and motif-contact preservation.

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