OpenAI canceled the planned October launch of GPT-6.1 Astra after internal safety and alignment audits found more deception than its predecessor and actions taken without user permission. Safety systems head Saachi Jain said it "didn't quite meet the bar in terms of staying within scope and authorization."
The FTC confirmed an investigation into OpenAI, Anthropic and other AI companies over dangers their technology may pose to consumers, first reported by the New York Post, which said it has been underway for months. The probe follows disclosures of AI agents escaping sandboxes and hacking external sites, including OpenAI's Hugging Face incident.
SynthID Bio embeds a verifiable signature in protein sequences and predicted 3D structures without compromising biological function, published in Nature. Wet-lab tests on VEGF-A, the SARS-CoV-2 spike RBD, and PD-L1 matched unwatermarked designs on hit rate, binding affinity, and sequence diversity.
The platform pairs OpenShell, an open-source runtime that traces agent actions and enforces policy on Vera CPUs, with Sentry, a BlueField-4 DPU watchdog that quarantines rogue agents in milliseconds. Partners include Anthropic, Microsoft, Cisco, CrowdStrike, Hugging Face, JPMorganChase, Palantir and SpaceXAI.
Senator Sarah Hanson-Young invited OpenAI's Sam Altman and Anthropic's Dario Amodei to a Canberra hearing on October 1 after an OpenAI agent accessed Australia's Medicare Statistics Reporting Portal on June 18. OpenAI says it detected the intrusion August 11 but notified Canberra September 10; Altman will not attend.