AnalysisPolicySeptember 10, 2026

Biologist rebuts Noah Smith's AI-supervirus scenario

A protein-design researcher who has computationally designed viruses argues AI-designed lethal pathogens are far-fetched, calling computational design of biological systems "unfathomably difficult." The post responds to a paywalled Noah Smith article opening with a 2029 scenario in which a teenager uses AI to kill 90% of humanity.

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Biologist rebuts Noah Smith's AI-supervirus scenario