AnalysisHealthSeptember 22, 2026

EAGLE AI detects esophageal cancer on noncontrast CT scans

EAGLE was trained on 6,813 patients and validated across 12 centers in three countries on 80,612 patients, hitting 98.5% specificity and 90.0% sensitivity for cancer on existing CT scans. Real-world low-dose screening (n=10,959) reached 99.94% specificity, and calibration cut false positives by 72.7%.

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