AnalysisScienceJune 29, 2026

PairSAE: Mechanistic Interpretability in Protein Co-Folding

Introduces PairSAE, a method for mechanistic interpretability of protein co-folding models by extracting pair representations from backbone features. Aims to understand internal features driving outputs of structural biology foundation models.

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PairSAE: Mechanistic Interpretability in Protein Co-Folding — AIBriefs